Margarita Deleuze began her artistic career drawing horses. Her work evolved from charcoals to oils and from painting horses to incorporating other animals and fruit in the realistic expression of her art. Her works are included in private collections in the United States, Europe and Latin America. 

Margarita Deleuze's oil paintings have been exhibited in solo and group exhibitions in galleries throughout the United States and abroad, as well as in the Florida Museum of Hispanic and Latin American Art in Miami, the Hortt Museum of Art in Fort Lauderdale and the San Francisco Museum of Contemporary Hispanic Art where she received an Honorable Mention. 

She has also participated in major exhibitions such as Art Expo '96 in Barcelona, Spain,  Art America '96 in Miami Beach Convention Center, Fl., Art Expo N.Y., the International Art Fair in her native Caracas, Venezuela; Art Expo 2000 in Coconut Grove Convention Center, Florida; as well as, shows in Livorno, Italy; Frankfurt, Germany; Washington, D.C.; and in Key Biscayne, Orlando, Coral Gables, and Naples, Florida. 

Ms. Deleuze is also the recipient of honors awarded by the Venezuelan American Association of University Women, as well as the "Premio Nosotros" awarded by ALAS in Miami, Florida; the Artistic Achievement Award of a five part national juried competition Artscape Naples 2003, Florida, Third Prize in the Weston Art Guild Juried Art Show in 2016 and Who's Who 2017 Albert Nelson Marquis Lifetime Achievement Award. She has had solo exhibitions in Caracas, Venezuela; Boca Raton, Florida; Miami, Florida; Sarasota, Florida; as well as, Santo Domingo, Dominican Republic and San Juan, Puerto Rico. She is featured in The Marquis Who's Who of American Women, Who's Who in America and Who's Who in the World, as well as in Strathmore's WHO'S WHO.

Margarita Deleuze is considered an international artist. Her name and inspiration come from France; her art formation from Latin America where she studied with Venezuelan masters; and her art has developed and evolved in the United States, where she now resides in Weston, Florida.